"The body's tendency to hold on to what we have [is] a brilliant survival strategy...Evolution could never have anticipated that we would have an abundance of energy [dense food] all the time. The system was designed for one environment that took millions of years to create, and now it's trying to cope with a radically different environment... Of course, that's really bad news for individuals with obesity, because they're fighting their biology, and their biology is, in effect, 24/7."

- Michael Lowe, hunger and obesity researcher, on how weight loss triggers biological backlash that relentlessly drives weight regain

Section: 1, Chapter: 6